Engineering Bioactive Nanomaterials for Drug Delivery and Bio-imaging
Lecturer: Prof. Sophia Gu
Time:11:00-11:30, July 7
Venue:Conference Room 242, Bio-tech building
Biography of Prof. Gu:
Dr Zi (Sophia) Gu is a Lecturer and National Health and Medicine Research Council (NHMRC) Research Fellow in the School of Chemical Engineering at University of New South Wales (UNSW), Sydney. She received her PhD in Biomedical Engineering from The University of Queensland (Australia) in 2011. In 2014, she commenced her NHMRC Fellowship, and secured a Lecturer position at UNSW in 2016. Dr Gu published 22 papers in high-impact journals including Advanced Materials (IF 19.791), Material Horizons (IF 10.706), Chemistry of Materials (IF 9.466), Biomaterials (IF 8.402), Journal of Controlled Release (IF 7.705), Chemical Communications (IF 6.319), etc. She has received AUD 600,000 in competitive funding as a Lead Chief Investigator. Very recently Dr Gu was awarded Monash Engineering Women’s Leadership Award. Her research group focuses on developing bioactive nanomaterials for drug delivery, biocatalysis and bio-imaging in disease therapy and diagnosis.
Nanomedicine, defined as the application of nanotechnology to medicine, is a relatively new yet rapidly evolving area, with a significant increase in the number of publications over the last 10 years. In contrast to conventional therapies where the basic approach is to remove diseased cells faster than healthy cells, nanomedicine formulations aim to kill or repair specific cells, tract drug release and monitor disease development, thus enabling personalised medicine. In this seminar, I will present our recent work on the development of (1) antibody-targeted drug-delivered clay nanosheets to prevent reblocking of artery (restenosis) and (2) manganese-based nano-clay as an ultrasensitive T1-magnetic resonance imaging contrast agent. This will be followed by discussion of the future developments in fabrication and application of nanomaterials for drug delivery in agricultural application and sensing for food safety.